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EVIDENCE | EBM Q: … “What Medical Evidence Is Available RE: Hydroxychloroquine (Plaquenil) and Azithromycin (Zithromax) as a treatment of COVID-19?”

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Question

“What Medical Evidence Is Available RE: Hydroxychloroquine (Plaquenil) and Azithromycin (Zithromax) as a treatment of COVID-19?”

Link(s) to Relevant Study(s)

  1. Published: 2020-03-20; Source: Authors: Philippe GAUTRET, Jean Christophe LAGIER, Philippe PAROLA, Van Thuan HOANG, Line MEDDED, Morgan MAILHE, Barbara DOUDIER, Johan COURJON, Valerie GIORDANENGO, Vera ESTEVES VIEIRA, Herve TISSOT DUPONT, Stephane HONORE, Philippe COLSON, Eric CHABRIERE, Bernard LA SCOLA, Jean Marc ROLAIN, Philippe BROUQUI, Didier RAOULT Sr.;

Summary (or Screen Shot) of Relevant Data Specific to Question

When comparing the effect of hydroxychloroquine treatment as a single drug and the effect of hydroxychloroquine and azithromycin combination, the proportion of patients that had negative PCR results in nasopharyngeal samples was significantly different between the two groups at days 3-4-5 and 6 post-inclusion. At day 6 post-inclusion, 100% of patients treated with hydroxychloroquine and azithromycin combination were virologicaly cured comparing with 57.1% in patients treated with hydroxychloroquine only, and 12.5% in the control group(p<0.001). These results are summarized in Figures 1 and 2. Source: Read Paragraph 2; Page 11 of PDF Here … https://www.medrxiv.org/content/10.1101/2020.03.16.20037135v1

Hydroxychloroquine and Azithromycin as a treatment of COVID-19: preliminary results of an open-label non-randomized clinical trial; page 11; paragraph 2 … This article is a preprint and has not been certified by peer review [what does this mean?]. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice. Source: medRxiv; March 2020
Evidenza | Call to Action FOR DOCTORS

“Physicians and Hospitals need to collect, share and publish accurate and recent data on the use of Hydroxychloroquine (Plaquenil) and Azithromycin (Zithromax) as a treatment for COVID-19.”

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