Treat-to-Target or High-Intensity Statin in Patients With Coronary Artery Disease (JAMA)

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Credit/Author:

JAMA. Published online March 6, 2023. doi:10.1001/jama.2023.2487

Importance

In patients with coronary artery disease, some guidelines recommend initial statin treatment with high-intensity statins to achieve at least a 50% reduction in low-density lipoprotein cholesterol (LDL-C). An alternative approach is to begin with moderate-intensity statins and titrate to a specific LDL-C goal. These alternatives have not been compared head-to-head in a clinical trial involving patients with known coronary artery disease.

Citation

Hong S, Lee Y, Lee S, et al. Treat-to-Target or High-Intensity Statin in Patients With Coronary Artery Disease: A Randomized Clinical Trial. JAMA. Published online March 06, 2023. doi:10.1001/jama.2023.2487

SOURCE: https://jamanetwork.com/journals/jama/fullarticle/2802214?guestAccessKey=f3627215-a166-44a1-88f9-4c34ab0c7fcf&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=030623

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