Pharmacogenomics is the study of how genes affect a person’s response to drugs. This relatively new field combines pharmacology (the science of drugs) and genomics (the study of genes and their functions) to develop effective, safe medications and doses that will be tailored to a person’s genetic makeup.
~ Genetics Home Reference – NIH
What might pharmacogenomics mean for you?
Until recently, drugs have been developed with the idea that each drug works pretty much the same in everybody. But genomic research has changed that “one size fits all” approach and opened the door to more personalized approaches to using and developing drugs.
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How is pharmacogenomic information being used today?
Doctors are starting to use pharmacogenomic information to prescribe drugs, but such tests are routine for only a few health problems. However, given the field’s rapid growth, pharmacogenomics is soon expected to lead to better ways of using drugs to manage heart disease, cancer, asthma, depression and many other common diseases.
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From the NHGRI’s Talking Glossary of Genetic Terms
- Pharmacogenomics Fact Sheet [nigms.nih.gov]
From the National Institute of General Medical Sciences
- What is pharmacogenomics? [ghr.nlm.nih.gov]
From Genetics Home Reference
- Pharmacogenomics [learn.genetics.utah.edu]
From the Genetic Science Learning Center
What is the difference between pharmacogenetics and pharmacogenomics?
The words pharmacogenomics and pharmacogenetics are often used interchangeably. … In general, pharmacogenetics usually refers to how variation in one single gene influences the response to a single drug. Pharmacogenomics is a broader term, which studies how all of the genes (the genome) can influence responses to drugs. ~Feb 16, 2014; MLO
PharmGKB, an internationally recognized scientific and clinical knowledge resource, has this definition on its website (http://www.pharmgkb.org/page/faqs):
What is the difference between pharmacogenetics and pharmacogenomics? In general, pharmacogenetics usually refers to how variation in one single gene influences the response to a single drug. Pharmacogenomics is a broader term, which studies how all of the genes (the genome) can influence responses to drugs.